6
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T62968 | PPARα/δ agonist 1 | ||
PPARα/δ agonist 1 is a potent PPARα/PPARδ dual agonist with EC50 values of 7.0 nM for PPARα and 8.4 nM for PPARδ. PPARα/δ agonist 1 exhibits high selectivity for PPARγ (EC50: 1316.1 nM). agonist 1 has potential for non-a... | |||
T37414 | CAY10771 | ||
CAY10771 is a dual agonist of farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor δ (PPARδ).1It activates FXR and PPARδ in reporter assays using HEK293T cells (EC50s = 0.94 and 1.5 μM, respectively)... | |||
T35800 | MD001 | ||
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. ... | |||
T35799 | MBX-8025 (sodium salt) | ||
MBX-8025 is an agonist of peroxisome proliferator-activated receptor δ (PPARδ).1 It is greater than 750- and 2,500-fold selective for PPARδ over PPARα and PPARγ. MBX-8025 (10 mg/kg per day for eight weeks) reduces increa... | |||
T35816 | ZLY032 | ||
ZLY032 is a dual agonist of free fatty acid receptor 1 (FFAR1/GPR40; EC50= 68 nM in a FLIPR assay) and peroxisome proliferator-activated receptor δ (PPARδ; EC50= 102 nM in a reporter assay).1It is selective for FFAR1 and... | |||
T14216 | AMG 837 | Others | |
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex... |